Santyl Collagenase (Enzymatic Ointment) - Healthpoint
Description: Santyl Collagenase digests collagen in necrotic tissue
Indications: debridement for chronic dermal ulcers including pressure ulcers, venous ulcers, arterial ulcers, diabetic foot ulcers, and severely burned areas. (Healthpoint, 2006)
Authors notes:
1. Slowest debridement ointment verses Accuzyme or Panafil
2. Less risk for pain or inflammation than with Accuzyme or Panafil
3. Can be used in a wound bed that has a combination of non-viable tissue along with granulation tissue and epithelization
4. Because Santyl doesn’t lead to inflammation, evidence suggests that (While slower to debride at first)the closure times of the wound are the same as papian based products (Brett, 2004).
5.Panafil and Accuzyme are not going to be made after January of 2009 (So Santyl may be the only ointment for debriding wounds)
6. For dry wounds that need to be debrided, use a moist primary dressing (hydrogel impregnated) to keep the Santyl from drying out.
Matthew Livingston R.N. C.W.S.